Mounting evidence indicates that the immune system and the brain worked together to protect early humans in a hostile ancestral environment rife with pathogens and predators. In modern times, however, chronic activation of the immune system may adversely affect the brain to cause depression. The most recent advances in this area of research were published by our group in a recent review in Nature Reviews Immunology. Read our article on inflammation and depression.

timePeople who are depressed are more likely to have exaggerated inflammatory responses to stressful situations, according to the results of a study released this week. Now, researchers want to know if that inflammation is behind the link between depression and heart disease … or if it’s the actual cause of depression.

Investigators from Emory University in Atlanta studied 28 otherwise healthy men. Half of the participants were diagnosed with major depression while the other half was depression-free.

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